Better Health Starts with
Human Connection.

Non-adherence is rarely a logistics problem. It’s an emotional one.

A patient can have the right medication, coverage, and reminders and still not take it. Closing that gap requires understanding why patients struggle and meeting them with the right support. 

— The Problem

Getting a patient to therapy is only the first step.

The industry has invested heavily in making therapy easier to obtain and start, but patients are still overwhelmed. The real challenge isn't just picking up the prescription — it's everything that happens after.

52%

of patients with a chronic condition said loneliness interfered with taking medications as prescribed1

70%

of patients on specialty medications said loneliness interfered with taking medications as prescribed1

1. Pleio Loneliness Survey, 2025. Conducted March 2025 in collaboration with PureSpectrum, engaging 2,008 U.S. adults who frequently experience loneliness and live with at least one chronic mental or physical health condition.


— How We Do It

Patient support, before and beyond first fill.

Brand persistence by fill number

1. Before First Fill

Many patients never fill their first prescription at all. We address hesitation before it ever becomes a lapse.

2. First 180 Days

Once therapy starts, adherence is often won or lost in the first six months. The GoodStart Adherence Program keeps one consistent voice in touch through that window, building lasting medication routines.

3. Ongoing — Additional Support

Titration guidance for dose changes, and win-back outreach for patients who've already lapsed.


— Program Architecture

What's Behind Every Conversation.

Connect

GoodStarters

The certified peer supporters behind every conversation, trained to build trust and rapport from the very first call.

Support

LIFT Platform

The technology behind every conversation, bringing structure and data science into the art of human engagement.

Activate

OLLIE AI

The intelligence behind every conversation, turning what patients say into signals your brand team can act on.


This is the first time I’ve ever gotten calls like this, somebody else outside family checking on me and I find that very soothing.”

“Nobody keeps tabs on you. It’s nice to know somebody is out there concerned about my diabetes and whether I’m taking my medication properly.” 

It’s nice to know that there’s somebody out there who knows that I’m taking this medication. Thank you so much.” 


For Pharmaceutical and Biotech Clients

Partner with Pleio to design a patient support program around your specific therapy area, patients, adherence, and brand challenges.

Explore Pharmaceutical Solutions
For Pharmacy Partners

Join our pharmacy network and help your patients start and stay on therapy at zero cost with zero disruption to your team.

Explore Pharmacy Partnerships
For Non-Pharmacy Partners

For hubs, patient support programs, health systems, electronic medical record systems, and platforms ready to embed human connection into a journey you've already built.

Explore Non-Pharmacy Partnerships
— Work With Pleio —

A new prescription can be overwhelming.

Pleio makes sure no patient faces it alone.

TALK TO OUR TEAM

WE PUT PRIVACY FIRST. GOODSTART® IS A FULLY TESTED, HIGHLY RELIABLE, TCPA, SOC 2 TYPE 2 CERTIFIED, AND HIPAA COMPLIANT MEDICATION SUPPORT PROGRAM.

Patient data is strictly used to support patients to take medications as prescribed by their healthcare professional.

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